This article is part of our FanDuel MLB series.
Wednesday's MLB main slate offers no shortage of selections, with 14 games on tap after 7:05 PM Eastern time that include every team except the Yankees and Tigers. Below, you'll find which individual pitchers and hitters are primed to provide the best value, as well as the top lineup stacking options in this slate.
While there's no shortage of teams in action, there are few elite pitchers taking the mound, making this more of a hitter-friendly slate. Of the two most expensive options, Sonny Gray ($10,200) has a far easier matchup against Seattle's 16th-ranked offense than Stephen Strasburg ($10,500) against the top-ranked Twins.
Reynaldo Lopez's ($8,600) season stats (5.17 ERA, 4.80 FIP) leave a lot to be desired, but the White Sox righty has displayed tremendous upside recently with nine innings of one-hit, 11-strikeout ball in Cleveland last time out and five no-hit innings at home against Texas two starts before that. Taking a risk on him against the 28th-ranked Royals offense could pay off in a big way.
Brewers righty Zach Davies ($6,900) won't give you many strikeouts (15.2 percent strikeout rate), but he's a high-floor option at Marlins Park against Miami's 29th-ranked offense. Davies has been stingy on the road, with a 2.83 ERA over 76.1 innings.
The Rays, Cardinals and Red Sox are all primed for strong offensive performances in hitter-friendly conditions, but there's plenty of value to be found outside of those three stackable lineups as well.
Padres third baseman Manny Machado ($3,500) has pulverized left-handed pitching this season to the tune of a .463 wOBA, and his success should continue against Cubs southpaw Cole Hamels, who has a 5.66 ERA and .356 wOBA allowed on the road.
Indians outfielder Jordan Luplow ($2,800) is another guy who's been fantastic against left-handed pitching, with a wOBA well over .400 in that split. The affordable right-handed slugger should continue that success against Angels starter Dillon Peters, who's giving up a .368 wOBA to batters from the right side.
Mets first baseman Pete Alonso ($4,200) is always a major home-run threat, having already launched 47 dingers in his fabulous rookie season. He has a great opportunity to go deep again here, as Diamondbacks starter Robbie Ray is allowing 1.70 HR/9 to batters from the right side and comes into this one battling a blister.
Rays vs. Ariel Jurado (Rangers)
This is a nearly ideal situation for Tampa's top hitters, as Globe Life Park in Arlington has the league's second-highest park factor (1.19) and Jurado comes in with a 5.40 ERA that climbs to 5.74 at home, along with a .376 home wOBA allowed. With the platoon advantage and a .395 wOBA against righties, Meadows should lead the charge against the vulnerable right-hander. Lowe is also a left-handed slugger and has excelled on the road with a wOBA over .400 away from Tropicana Field. Adames' .416 road wOBA in righty-on-righty matchups is equal to Jurado's home wOBA allowed in that split.
Cardinals vs. Antonio Senzatela (Rockies)
The only venue with a more hitter-friendly tilt than Globe Life Park this season is Coors Field, which boasts an astronomical 1.44 park factor. St. Louis' offense should have a field day there against Senzatela, who has a 7.19 ERA in 21 starts overall and a 10.34 mark over his last 10. Wong has the platoon advantage against the righty as a left-handed batter and boasts a .390 road wOBA. Ozuna has a .360 wOBA in righty-on-righty matchups, with 21 of his 26 home runs coming in that split. The switch-hitting Fowler will maximize his plate appearances out of the leadoff spot and should be extra motivated to deliver against the team he played for from 2008-2013.
Red Sox vs. Trent Thornton (Blue Jays)
Every game is a must-win for a Boston team that's an extreme long shot to make the playoffs, so the fourth-ranked Red Sox offense won't take its foot off the gas against Thornton, who has a 5.23 ERA and 4.89 FIP. Left-handed batters have a .387 wOBA against Thornton at Rogers Centre, and Devers and Benintendi are more dangerous than most hitters from that side. Devers has a .409 wOBA against righties, while Benintendi's OPS over the past 40 games is just a hair under .900. Betts has done his best work in righty-on-righty situations this season, posting a .389 wOBA.